Genomic Imprinting and Human Disease.

Genomic Imprinting and Human Reproduction

Genomic Imprinting in Human Placenta

Luca Lambertini1,2, Men-Jean Lee3, Carmen J. Marsit4 and Jia Chen1,5,6 1Department of Preventive Medicine, Mount Sinai School of Medicine, New York, 2Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai School of Medicine, New York, 3Department of Obstetrics and Gynecology, Indiana University-Purdue University, Indianapolis, 4Department of Pharmacology and Toxicology, Dart...

Genomic imprinting and environmental disease susceptibility.

Genomic imprinting is one of the most intriguing subtleties of modern genetics. The term "imprinting" refers to parent-of-origin-dependent gene expression. The presence of imprinted genes can cause cells with a full parental complement of functional autosomal genes to specifically express one allele but not the other, resulting in monoallelic expression of the imprinted loci. Genomic imprinting...

Genomic Imprinting

BACKGROUND Genomic imprinting is the inheritance out of Mendelian borders. Many of inherited diseases and human development violates Mendelian law of inheritance, this way of inheriting is studied by epigenetics. AIM The aim of this review is to analyze current opinions and options regarding to this way of inheriting. RESULTS Epigenetics shows that gene expression undergoes changes more com...

Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated...